Compound Monograph

Anhalonine

Anhalonine is a minor tetrahydroisoquinoline alkaloid of peyote and related mescaline-bearing cacti.

Classification

Anhalonine is a tetrahydroisoquinoline alkaloid, part of the alkaloids class. Nitrogen-containing, often bitter and physiologically potent compounds — the group behind many of the strongest plant medicines and poisons.

Where Does It Come From? (1)

Anhalonine is a naturally occurring tetrahydroisoquinoline alkaloid, found in Peyote. It is flagged as moderately toxic.

Peyote

Research & Evidence

Anhalonine is a minor tetrahydroisoquinoline alkaloid identified in peyote (Lophophora williamsii) and related cacti, where it occurs alongside mescaline and other isoquinoline alkaloids. It is one of a group of structurally related minor constituents rather than a primary psychoactive agent, and little is firmly established about its individual effects in humans.

Toxicity & Safety

Isolated anhalonine has not been well studied, and its safety profile in humans is not clearly characterised outside its presence as a minor component of peyote.