Compound Monograph
Azelaic acid
Azelaic acid is a nine-carbon dicarboxylic acid produced naturally on skin and used in dermatology.
Where Does It Come From? (1)
Azelaic acid is a naturally occurring (and made in the body) dicarboxylic acid, found in Whole grains. It is well tolerated orally (low toxicity).
Research & Evidence
Azelaic acid is a saturated nine-carbon dicarboxylic acid that occurs naturally in whole grains such as wheat, rye and barley and is also produced on human skin by yeasts of the genus Malassezia. In dermatology it is used topically for conditions such as acne and rosacea, where it has antibacterial and keratin-normalising effects and can help even out skin tone.
Toxicity & Safety
Topical azelaic acid is generally well tolerated and low in toxicity; the most common effects are mild local irritation, stinging or dryness at the site of application. It is a recognised cosmetic and dermatological ingredient.