Compound Monograph

Capreomycin

Capreomycin is a cyclic peptide antibiotic produced by a soil bacterium and used as a second-line drug against tuberculosis.

Where Does It Come From? (1)

Capreomycin is a naturally occurring (and made in the body) cyclic peptide antibiotic, found in Soil bacterium. It is flagged as moderately toxic.

Soil bacterium

Research & Evidence

Capreomycin is a cyclic peptide antibiotic originally isolated from the soil bacterium Streptomyces capreolus (now Saccharothrix mutabilis subsp. capreolus). It inhibits bacterial protein synthesis and is used as an injectable second-line agent in the treatment of multidrug-resistant tuberculosis, generally as part of a combination regimen under specialist supervision.

Toxicity & Safety

Capreomycin is a prescription antibiotic with notable toxicity rather than a casual supplement. Its main risks are kidney damage and harm to the inner ear, which can cause hearing loss and balance problems, and it can disturb electrolyte levels. It is given by injection under medical monitoring and is not appropriate for self-administration.