Compound Monograph
Galbulimima alkaloids (galbulimima A, B, and C)
A family of complex polycyclic alkaloids isolated from the bark of the Australasian tree Galbulimima belgraveana.
Where Does It Come From? (1)
Galbulimima alkaloids (galbulimima A, B, and C) is a naturally occurring polycyclic alkaloid, found in Galbulimima. It is flagged as moderately toxic.
Research & Evidence
The galbulimima alkaloids are a group of structurally intricate polycyclic alkaloids obtained from the bark of Galbulimima belgraveana, a rainforest tree native to New Guinea and northern Australia. Bark preparations of this tree have a history of traditional use in Papua New Guinea, and the alkaloids have attracted interest from synthetic chemists because of their elaborate ring systems. Beyond their isolation and structural characterisation, little is firmly established about their pharmacology in humans.
Toxicity & Safety
The human safety profile of these individual alkaloids is not well characterised. Traditional bark preparations from the source tree have reputed psychoactive effects, but reliable dose-response and toxicity data are lacking.