Compound Monograph
LSA (Ergine)
LSA (ergine) is a naturally occurring lysergamide alkaloid found in morning glory and Hawaiian baby woodrose seeds.
Where Does It Come From? (3)
LSA (Ergine) is a naturally occurring ergot (lysergamide) alkaloid, found in Morning glory, Hawaiian baby woodrose and Sleepy grass and certain ergot fungi. It is flagged as moderately toxic and psychedelic.
Research & Evidence
LSA, or ergine (d-lysergic acid amide), is a naturally occurring ergoline alkaloid closely related to LSD but considerably less potent and with a different character. It is the main psychoactive constituent of the seeds of morning glory and Hawaiian baby woodrose, which have a long history of traditional and recreational use. Its effects are typically described as dreamy, sedating and mildly psychedelic, often accompanied by heavy physical relaxation, rather than the bright, energetic quality associated with LSD.
Toxicity & Safety
The seeds containing LSA frequently cause nausea, vomiting and vasoconstriction, and as ergoline alkaloids they can constrict blood vessels, which is a concern for people with cardiovascular conditions or those taking other vasoactive or serotonergic drugs. Commercially sold seeds are also often coated with fungicides intended to deter ingestion, which add their own toxicity. It is controlled in the United States.