Compound Monograph

Methcathinone

Methcathinone is a potent stimulant of the cathinone class, structurally related to methamphetamine and to natural cathinone.

Where Does It Come From?

Methcathinone is a naturally occurring cathinone (substituted phenethylamine). It is flagged as toxic.

Research & Evidence

Methcathinone is a synthetic-feeling but naturally related stimulant of the cathinone family, structurally the β-keto analogue of methamphetamine and the N-methyl analogue of cathinone (the active stimulant of khat, Catha edulis). It acts as a releaser of dopamine and noradrenaline, producing strong stimulant and euphoric effects. It has a significant history of illicit manufacture and abuse.

Toxicity & Safety

Methcathinone carries the typical risks of potent stimulants, including cardiovascular strain, agitation and dependence. Illicitly produced material made with permanganate has additionally been linked to manganese-induced neurological damage. It is a Schedule I substance in the United States.