Compound Monograph

N-Methyltyramine

N-Methyltyramine is a trace-amine alkaloid and the N-methyl derivative of tyramine, found in barley and citrus.

Classification

N-Methyltyramine is a phenethylamine alkaloid (trace amine), part of the alkaloids class. Nitrogen-containing, often bitter and physiologically potent compounds — the group behind many of the strongest plant medicines and poisons.

Where Does It Come From? (3)

N-Methyltyramine is a naturally occurring phenethylamine alkaloid (trace amine), found in Common reed, Barley and Bitter orange. It is flagged as moderately toxic.

BarleyBitter orangeCommon reed

N-Methyltyramine is the N-methyl derivative of tyramine, a trace amine occurring in germinating barley, citrus and other plants, and a biosynthetic precursor to hordenine. It acts as an indirect sympathomimetic and appears in some sports and weight-management supplements, though specific human evidence is limited.