Compound Monograph

Valerenic acid

A sesquiterpene acid that is the characteristic marker of valerian root; it modulates GABA-A receptors and is regarded as a main contributor to valerian’s sedative and anxiolytic effects.

Classification

Valerenic acid is one of the sesquiterpenes, part of the terpenoids class. The largest class of plant compounds, built from five-carbon isoprene units — the essential-oil aromatics, resins, bitter principles, saponins, and plant sterols.

Where Does It Come From? (1)

Valerenic acid is one of the sesquiterpenes, found in Valerian.