Compound Monograph

7-Hydroxymitragynine

A minor indole alkaloid of kratom and an active metabolite of mitragynine that binds mu-opioid receptors more strongly than its parent; a potent opioid agonist and the main driver of kratom’s analgesic and dependence-related effects.

Classification

7-Hydroxymitragynine is one of the indole alkaloids, part of the alkaloids class. Nitrogen-containing, often bitter and physiologically potent compounds — the group behind many of the strongest plant medicines and poisons.

Where Does It Come From? (1)

7-Hydroxymitragynine is one of the indole alkaloids, found in Kratom. It is flagged as moderately toxic and psychedelic.