Compound Monograph
Cichoric acid
Cichoric acid is a phenolic acid (caffeic acid derivative) used as a marker compound in Echinacea.
Classification
Cichoric acid is a phenolic acid (hydroxycinnamic acid derivative), part of the phenolics class. Antioxidant compounds built around one or more phenol rings — the flavonoids, tannins, phenolic acids, coumarins, and pigments behind much of a plant's protective chemistry.
Where Does It Come From? (4)
Cichoric acid is a naturally occurring phenolic acid (hydroxycinnamic acid derivative), found in Purple coneflower, Chicory and 2 other sources. It is well tolerated orally (low toxicity).
Research & Evidence
Cichoric acid is a phenolic acid built from two units of caffeic acid joined to tartaric acid. It is found in chicory, from which it takes its name, and in purple coneflower (Echinacea purpurea), where it is one of the marker compounds used to assess the quality of Echinacea preparations. Laboratory studies report antioxidant and immunomodulatory activity, and it is frequently discussed in the context of Echinacea’s traditional use for immune support.
Toxicity & Safety
Cichoric acid is a dietary phenolic acid found in foods such as chicory and in Echinacea preparations with a long history of use, and it is not regarded as notably toxic. A detailed isolated-compound safety profile has not been well established.