Compound Monograph

Cnicin

An intensely bitter germacranolide sesquiterpene lactone that is the principal active constituent of blessed thistle; its bitterness stimulates digestion, and it shows anti-inflammatory and antimicrobial activity.

Classification

Cnicin is one of the sesquiterpene lactones, part of the terpenoids class. The largest class of plant compounds, built from five-carbon isoprene units — the essential-oil aromatics, resins, bitter principles, saponins, and plant sterols.

Where Does It Come From? (3)

Cnicin is one of the sesquiterpene lactones, found in Blessed thistle, Centaury and Cornflower.

Blessed thistleCentaury Cornflower Centaurea cyanus