Compound Monograph
Scutellarin
Scutellarin is a flavone glycoside from skullcap and Erigeron, marketed in some regions as breviscapine for cardiovascular and cerebrovascular conditions.
Classification
Scutellarin is a flavonoid (flavone glycoside), part of the phenolics class. Antioxidant compounds built around one or more phenol rings — the flavonoids, tannins, phenolic acids, coumarins, and pigments behind much of a plant's protective chemistry.
Where Does It Come From? (4)
Scutellarin is a naturally occurring flavonoid (flavone glycoside), found in Skullcap, Erigeron breviscapus and 2 other sources. It is well tolerated orally (low toxicity).
Research & Evidence
Scutellarin is the glucuronide of scutellarein, a flavone glycoside found in skullcap and in Erigeron breviscapus. In China it is used as a standardised extract (breviscapine) and has been investigated for cerebrovascular and cardiovascular indications, with reported effects on blood flow and platelet activity. Much of the supporting evidence comes from regional clinical and preclinical research.
Toxicity & Safety
Scutellarin is generally well tolerated in the preparations in which it has been studied. Detailed toxicology in the general population is limited, and it has not been formally characterised for interactions with conventional medicines.