Compound Monograph
Tetrahydroharman
Tetrahydroharman is a beta-carboline alkaloid found in various plants, structurally related to harman and the harmala alkaloids.
Classification
Tetrahydroharman is a beta-carboline alkaloid, part of the alkaloids class. Nitrogen-containing, often bitter and physiologically potent compounds — the group behind many of the strongest plant medicines and poisons.
Where Does It Come From? (3)
Tetrahydroharman is a naturally occurring beta-carboline alkaloid, found in Common reed, Russian olive and 1 other source. It is flagged as moderately toxic.
Research & Evidence
Tetrahydroharman is a beta-carboline alkaloid, the tetrahydro analog of harman, found in plants such as common reed and Russian olive (the source of the synonym elaeagnine). Beta-carbolines of this type are studied for their interactions with monoamine systems, but tetrahydroharman specifically is not well characterised in humans.
Toxicity & Safety
The human safety profile of tetrahydroharman is not well established. As with related beta-carbolines, its interaction with monoamine metabolism warrants caution.