Compound Monograph
Zeaxanthin
Zeaxanthin is a yellow xanthophyll carotenoid concentrated, with lutein, in the macula of the eye.
Where Does It Come From? (3)
Zeaxanthin is a naturally occurring carotenoid (xanthophyll), found in Calendula, Corn and Leafy greens. It is well tolerated orally (low toxicity).
Research & Evidence
Zeaxanthin is a yellow-pigmented xanthophyll, one of the oxygen-containing carotenoids, and is closely related to lutein as one of its isomers. In humans it is concentrated together with lutein in the macula of the retina, where these pigments absorb blue light and are thought to help protect the eye from oxidative and light-related stress. It is obtained from the diet via corn, leafy greens and brightly coloured plants such as calendula, and has been studied in the context of eye health and age-related macular degeneration.
Toxicity & Safety
Zeaxanthin is a normal dietary carotenoid consumed in foods and is generally considered to have low toxicity; very high carotenoid intake can cause harmless yellowing of the skin. It is widely used in eye-health supplements.