Compound Monograph
Allocryptopine
Allocryptopine is a protopine-type isoquinoline alkaloid found in California poppy and other plants of the poppy and fumitory families.
Classification
Allocryptopine is an isoquinoline alkaloid (protopine type), part of the alkaloids class. Nitrogen-containing, often bitter and physiologically potent compounds — the group behind many of the strongest plant medicines and poisons.
Where Does It Come From? (3)
Allocryptopine is a naturally occurring isoquinoline alkaloid (protopine type), found in California poppy, Greater celandine and Plume poppy. It is flagged as moderately toxic.
Research & Evidence
Allocryptopine is a protopine-type isoquinoline alkaloid that occurs in California poppy and other members of the poppy (Papaveraceae) and related families. It is one of several minor alkaloids in these plants and has been studied chiefly for cardiac and ion-channel activity in laboratory settings. Beyond its identification as a constituent and these preliminary pharmacological observations, little is firmly established about its effects in humans.
Toxicity & Safety
The isolated compound has not been well characterised for human safety. As a plant alkaloid with reported activity on cardiac ion channels, it is best regarded with caution, though it is normally encountered only as a minor constituent of whole-plant preparations rather than on its own.