Compound Monograph
Diosmetin
Diosmetin is a flavone (the aglycone of diosmin) found in herbs such as rosemary and hyssop and in citrus.
Classification
Diosmetin is a flavonoid (flavone), part of the phenolics class. Antioxidant compounds built around one or more phenol rings — the flavonoids, tannins, phenolic acids, coumarins, and pigments behind much of a plant's protective chemistry.
Where Does It Come From? (5)
Diosmetin is a naturally occurring flavonoid (flavone), found in Rosemary, Hyssop, Citrus fruits and 2 other sources. It is well tolerated orally (low toxicity).
Research & Evidence
Diosmetin is a methoxylated flavone and the aglycone of the glycoside diosmin. It occurs in a range of aromatic herbs, including rosemary and hyssop, and in citrus. Like related dietary flavonoids it has been examined in laboratory studies for antioxidant and other bioactivities, but well-defined clinical roles for the isolated compound are limited.
Toxicity & Safety
As a minor flavonoid of common culinary herbs and fruits, dietary exposure to diosmetin is generally regarded as low risk; its isolated safety profile has not been extensively characterised.