Compound Monograph

Orientin

Orientin is a C-glycosylated flavone (the 8-C-glucoside of luteolin) found in plants such as holy basil and rooibos.

Classification

Orientin is a flavonoid (flavone c-glycoside), part of the phenolics class. Antioxidant compounds built around one or more phenol rings — the flavonoids, tannins, phenolic acids, coumarins, and pigments behind much of a plant's protective chemistry.

Where Does It Come From? (7)

Orientin is a naturally occurring flavonoid (flavone c-glycoside), found in Holy basil / tulsi, Rooibos, Passionflower and 4 other sources. It is well tolerated orally (low toxicity).

Research & Evidence

Orientin is a flavone C-glycoside, specifically the 8-C-glucoside of luteolin. It is a common dietary flavonoid found in holy basil, rooibos, passionflower, millet and other plants. Because the sugar is attached through a carbon–carbon bond, it is more resistant to hydrolysis than ordinary O-glycosides. Like related flavonoids it has been studied mainly for antioxidant and anti-inflammatory activity in laboratory and animal models.

Toxicity & Safety

Orientin occurs in commonly consumed herbs and teas and is considered low in toxicity at dietary levels. It has not been individually characterised in detail in humans.