Compound Monograph
Tetrahydrocannabivarin
THCV is a minor cannabis cannabinoid structurally similar to THC but with a shorter side chain and distinct effects.
Sources · 1
Where Does It Come From?
Tetrahydrocannabivarin is a naturally occurring cannabinoid, found in Hemp and Marijuana. It is flagged as moderately toxic.
Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
Tetrahydrocannabivarin (THCV) is a minor cannabinoid found in cannabis, differing from THC by a shorter propyl side chain. Its pharmacology differs from THC: at lower amounts it can behave as a CB1 receptor antagonist, while at higher amounts it may act as an agonist. It has attracted research interest in connection with appetite and metabolic effects, though human evidence remains limited.
Toxicity & Safety
THCV is generally considered to have a relatively mild profile, but it is not thoroughly characterized in humans, and its effects depend on dose. As with other cannabinoids, caution is reasonable.
