Compound Monograph
Corticotrophin
Corticotrophin (ACTH) is a peptide hormone from the pituitary gland that stimulates the adrenal glands.
Sources · 1
Where Does It Come From?
Corticotrophin is a naturally occurring (and made in the body) polypeptide hormone, found in Pituitary gland. It is flagged as moderately toxic.
Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
Corticotrophin, better known as adrenocorticotropic hormone (ACTH), is a peptide hormone produced by the anterior pituitary gland. It stimulates the adrenal cortex to release corticosteroid hormones such as cortisol and is a central part of the body’s stress-response axis. Preparations of ACTH are used medically as a diagnostic agent for adrenal function and, in some conditions, therapeutically.
Toxicity & Safety
As a hormone that drives corticosteroid release, therapeutic use of corticotrophin carries the effects and risks associated with raised steroid levels, including effects on blood sugar, blood pressure, mood and the immune system. It is a prescription medicine used under medical supervision.
