Compound Monograph

Echinacein

Lipids & Fatty Acids Natural (plant-derived)

Echinacein is an alkylamide (alkamide) from purple coneflower (Echinacea) associated with the tingling sensation of the herb.

Sources · 2

Where Does It Come From?

Echinacein is a naturally occurring alkylamide (alkamide), found in Purple coneflower and Other Echinacea species. It is well tolerated orally (low toxicity).

Also found in
Other Echinacea species Monograph coming soon
Purple coneflower Monograph coming soon

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Research & Evidence

Echinacein is an unsaturated isobutylamide (alkamide) from Echinacea species, the purple coneflowers used in traditional and over-the-counter herbal preparations. Alkamides of this kind are responsible for the characteristic tingling, numbing sensation of Echinacea root and are among the constituents studied in connection with the plant’s immune-related and other effects, though evidence for the isolated compound is limited.

Toxicity & Safety

As a constituent of a widely consumed herbal supplement, echinacein is generally regarded as low risk; its isolated safety profile has not been well characterized.