Compound Monograph
N-Isobutyl-2E,4E-decadienamide
Pellitorine — a pungent Echinacea alkylamide, also found in pellitory and the peppers. The N-isobutylamide of 2E,4E-decadienoic acid.
Sources · 3
Where Does It Come From?
N-Isobutyl-2E,4E-decadienamide is a naturally occurring fatty acid amide (n-alkylamide), found in Echinacea, Pellitory and Long pepper and related Piper species. It is well tolerated orally (low toxicity).
Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
This is an N-isobutyl alkylamide of decadienoic acid, a member of the alkylamide family characteristic of Echinacea roots; the 2E,4E isomer corresponds to the compound known as pellitorine, which also occurs in other pungent plants. Echinacea alkylamides are studied for their tingling sensory effect and for proposed immune-modulating and cannabinoid-receptor activity in laboratory models. Specific human data on this single constituent are limited.
