Compound Monograph
Isoergine
Isoergine is an ergot-type lysergamide alkaloid found in morning glory and related seeds, an epimer of ergine (LSA).
Sources · 3
Where Does It Come From?
Isoergine is a naturally occurring ergot (lysergamide) alkaloid, found in Morning glory, Hawaiian baby woodrose and 1 other source. It is flagged as moderately toxic and psychedelic.
Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
Isoergine is a naturally occurring lysergamide (ergoline) alkaloid found in the seeds of morning glory and related plants, where it occurs together with ergine (LSA). It is the iso, or epimeric, form of ergine, differing in the configuration at one position of the lysergic acid skeleton. It is generally considered less active than ergine, and it forms part of the mixture of ergoline alkaloids responsible for the sedating, mildly psychedelic effects historically associated with these seeds.
Toxicity & Safety
As an ergoline alkaloid, isoergine occurs in seeds that can also cause nausea, vasoconstriction and unpleasant physical effects, and morning glory seeds are frequently treated with fungicides that add their own hazards. Its individual safety profile is not well characterized.
