Compound Monograph

Lobelidine

Alkaloids Other Alkaloids Natural (plant-derived)

Lobelidine is a minor piperidine alkaloid of Lobelia, structurally related to lobeline.

Sources · 1

Where Does It Come From?

Lobelidine is a naturally occurring piperidine alkaloid, found in Lobelia. It is flagged as moderately toxic.

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Research & Evidence

Lobelidine is a minor piperidine alkaloid of Lobelia inflata, one of a family of related Lobelia alkaloids that includes lobeline, lobelanine and lobelanidine. (Although some records cross-label it with lobeline, lobelidine is a distinct compound.) Little is established about it independently of the wider alkaloid group.

Toxicity & Safety

Like the other Lobelia alkaloids, lobelidine warrants caution given the genus’s history of emetic and nicotinic effects. Its individual safety profile has not been characterized.