Compound Monograph
Noradrenaline
Noradrenaline is a catecholamine that functions as both a neurotransmitter and a hormone in the human "fight-or-flight" response.
Sources · 3
Where Does It Come From?
Noradrenaline is a naturally occurring (and made in the body) catecholamine, found in Velvet bean, Endogenous in humans and animals and 1 other source. It is flagged as moderately toxic.
Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
Noradrenaline (norepinephrine) is a catecholamine produced in the body from dopamine. It acts both as a neurotransmitter in the sympathetic nervous system and brain and as a hormone released from the adrenal glands. By stimulating adrenergic receptors it increases heart rate, blood pressure and alertness, and it plays a central role in the body’s arousal and stress responses. It is also used clinically as a vasopressor in critical care. Although primarily an endogenous compound, traces occur in some plants, such as velvet bean.
Toxicity & Safety
Noradrenaline is a potent, tightly regulated signaling molecule rather than a casual supplement. As a medicine it is given only intravenously under close monitoring, because excessive adrenergic stimulation can cause dangerous rises in blood pressure and heart rhythm disturbances. It is not orally active in any meaningful recreational sense.
