Compound Monograph

Oripavine

Alkaloids Isoquinoline Alkaloids Natural (plant-derived)

Oripavine is a minor opium poppy alkaloid and a chemical precursor used in the synthesis of stronger opioids.

Sources · 1

Where Does It Come From?

Oripavine is a naturally occurring morphinan opium alkaloid, found in Opium poppy. It is flagged as toxic.

Also found in
Opium poppy Monograph coming soon

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Oripavine is a minor alkaloid of the opium poppy (Papaver somniferum) and the O-demethylated relative of thebaine. It has opioid activity itself but is of greatest practical importance as a chemical intermediate in the manufacture of semisynthetic opioids. Like other potent opioids it carries serious risks of respiratory depression and dependence, and it is a Schedule II controlled substance in the United States.