Compound Monograph

Tabernanthine

Alkaloids Indole Alkaloids Natural (plant-derived)

Tabernanthine is an iboga-type indole alkaloid related to ibogaine, found in plants of the genus Tabernanthe.

Sources · 1

Where Does It Come From?

Tabernanthine is a naturally occurring iboga-type indole alkaloid, found in Iboga. It is flagged as moderately toxic.

Also found in
Iboga Monograph coming soon

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Research & Evidence

Tabernanthine is an iboga-type indole alkaloid structurally related to ibogaine and found in Tabernanthe species. Like other iboga alkaloids it has been studied chiefly in a pharmacological context, but it is far less characterized than ibogaine and relatively little about its effects in humans is firmly established.

Toxicity & Safety

Iboga alkaloids as a class can affect cardiac conduction, and the safety profile of tabernanthine specifically is not well characterized. Caution is warranted.