Compound Monograph
3-Methoxytyramine
3-Methoxytyramine is a trace amine and a metabolite of the neurotransmitter dopamine.
Sources · 3
Where Does It Come From?
3-Methoxytyramine is a naturally occurring (and made in the body) catecholamine metabolite (trace amine), found in Mammalian tissue and 2 other sources. It is well tolerated orally (low toxicity).
Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
3-Methoxytyramine (3-MT) is a trace amine formed in the body when the enzyme catechol-O-methyltransferase methylates dopamine. It is best known as one of the markers used to study dopamine metabolism, and measured levels of 3-MT and related metabolites are sometimes used in research and clinical chemistry as an index of catecholamine turnover. It has only weak direct activity of its own compared with the parent neurotransmitter.
Toxicity & Safety
As an endogenous dopamine metabolite present in trace amounts, 3-methoxytyramine is not regarded as a toxic compound under normal physiological conditions, and it is not used recreationally.
