Compound Monograph

Anhalonidine

Alkaloids Isoquinoline Alkaloids Natural (plant-derived)

Anhalonidine is a tetrahydroisoquinoline alkaloid found in peyote and related cacti.

Sources · 3

Where Does It Come From?

Anhalonidine is a naturally occurring tetrahydroisoquinoline alkaloid, found in Peyote and 2 other sources. It is flagged as moderately toxic.

Also found in
Peyote Monograph coming soon
San Pedro cactus Monograph coming soon

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Research & Evidence

Anhalonidine is one of the minor tetrahydroisoquinoline alkaloids of peyote (Lophophora williamsii), accompanying the cactus’s principal psychoactive component, mescaline. It belongs to the same chemical family as several other peyote constituents such as anhalonine and pellotine. It is not considered a major contributor to peyote’s psychedelic effects, and little is firmly established about its activity in humans on its own.

Toxicity & Safety

There is limited human safety data on isolated anhalonidine. As a minor cactus alkaloid it has not been well characterized pharmacologically or toxicologically outside its natural occurrence within peyote.