Compound Monograph
Lutein
Lutein is a yellow xanthophyll carotenoid that concentrates in the macula of the eye and is widely consumed from leafy greens and marigold.
Sources · 7
Where Does It Come From?
Lutein is a naturally occurring carotenoid (xanthophyll), found in Calendula, Mexican tarragon, Marigold and 4 other sources. It is well tolerated orally (low toxicity).
Principal source Calendula Calendula officinalis Herb monograph → 
Source Guayusa Ilex guayusa Herb monograph → 
Source Mexican Tarragon Tagetes lucida Herb monograph → Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
Lutein is a yellow xanthophyll carotenoid found abundantly in dark leafy greens, egg yolk and marigold flowers (a major commercial source). Along with its isomer zeaxanthin, lutein selectively accumulates in the macula of the retina, where the two form the macular pigment that filters blue light and acts as an antioxidant. Lutein and zeaxanthin have therefore been studied extensively in connection with eye health, particularly age-related macular degeneration; large trials of carotenoid supplementation have informed dietary recommendations, although results are nuanced. Lutein is also used as a natural food and feed colorant.
Toxicity & Safety
Lutein is a normal dietary carotenoid with a long record of safe consumption and is regarded as low in toxicity. Very high intakes can cause a harmless yellowish tint to the skin (carotenodermia). It is widely used in supplements and is generally well tolerated.
