Compound Monograph

Nornicotine

Alkaloids Other Alkaloids Natural (plant-derived)

Nornicotine is a minor tobacco alkaloid and the demethylated analogue and metabolite of nicotine.

Sources · 2

Where Does It Come From?

Nornicotine is a naturally occurring pyridine–pyrrolidine alkaloid, found in Tobacco and 1 other source. It is flagged as toxic.

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Nornicotine is a minor alkaloid of tobacco and also a metabolite of nicotine, from which it differs by lacking the N-methyl group. It is pharmacologically active at nicotinic acetylcholine receptors, though generally weaker than nicotine, and like other tobacco alkaloids should be treated as toxic.