Compound Monograph

Thunberginol C

Phenolics Coumarins Natural (plant-derived)

An Asian-hydrangea-leaf isocoumarin identified as an active behind an anxiolytic and neuroprotective extract signal.

Sources · 1

Where Does It Come From?

Thunberginol C is a naturally occurring isocoumarin, found in Hydrangea — Asian leaf. Its toxicity is not yet characterized.

Also found in
Hydrangea — Asian leaf Monograph coming soon

Concentration

Content by Source

Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.

Research & Evidence

Thunberginol C is an isocoumarin of Asian hydrangea leaf. Oral H. macrophylla extract protected cortical neurons against corticosterone toxicity and reduced restraint-stress anxiety in mice, with thunberginol C identified as an active ingredient; a cholinesterase-inhibition signal is also reported. This is a small cluster of single studies, and — as with thunberginol A — it is Asian-leaf work, not H. arborescens.

Toxicity & Safety

No isolated-compound toxicity dataset exists. The species caveat above applies.

Placeholder entry — a full monograph is pending via the compound-expansion worklist.