Compound Monograph
Harpagide
An iridoid glycoside found in wood betony and devil's claw, related to the bitter constituents of those herbs.
Sources · 3
Where Does It Come From?
Harpagide is a naturally occurring iridoid glycoside, found in Wood betony, Devil's claw and 1 other source. It is well tolerated orally (low toxicity).
Principal source Wood Betony Stachys officinalis Herb monograph → 
Source Devil's Claw Harpagophytum procumbens Herb monograph → Concentration
Content by Source
Concentrations not reported. No percent-dry-weight or mg/g figures have been published for this compound in its source plants.
Research & Evidence
Harpagide is an iridoid glycoside present in wood betony and in devil’s claw (Harpagophytum), from which it takes its name. It belongs to the same family of bitter iridoids as harpagoside and is studied chiefly as part of the phytochemical profile of those herbs, which are used traditionally for inflammatory and musculoskeletal complaints. Information specific to the isolated compound is limited.
Toxicity & Safety
Harpagide has not been characterized in detail for safety as an isolated compound. The herbs containing it are generally regarded as well tolerated in customary use.
