Condition

Epilepsy

Epilepsy is a neurological disorder characterized by recurrent seizures caused by abnormal electrical activity in the brain.

Overview

Aetiology

There are many different causes for epilepsy. The most common cause in infancy includes hypoxic-ischemic encephalopathy. This accounts for roughly 40-60% of cases. Ischemia results with injury to the gray and white matter of the brain.

Other causes include head trauma, strokes, vascular dysfunctions, cortical dysplasia, CNS infection, cancer, and Ammon’s horn sclerosis 1Reference 1Beghi · 2004Aetiology of epilepsy (p. It’s a disorder of the excitatory and inhibitory neurotransmitters in the brain (glutamate/aspartate & GABA).

Jacksonian Seizures

Localized seizure in one part of the brain. this often results in a single limb or muscle group spasming for a few moments.

Petit-Mal Seizures

Also known as an abscence seizure. It involves a sudden loss of attention, causing someone to stare off blankly for a few moments to a few minutes. this type of seizure may remain in one hemisphere of the brain, and the patient may remain conscious.

Grand-Mal Seizures

Involves full-body convulsions and a loss of consciousness. This type of seizure always affects both hemispheres of the brain.

Presentation

Symptoms

Symptoms vary with seizure type and may include temporary confusion, staring spells, loss of awareness, stiffening or jerking movements of the limbs, loss of consciousness, and unusual sensations or auras preceding an episode. Some seizures involve falling, tongue biting, or loss of bladder control.

Assessment

Diagnostic Considerations

  • Electroencephalogram (EEG)

  • High-density EEG

  • Scans

    • Computerized tomography (CT) scan
    • Magnetic resonance imaging (MRI)
    • Functional MRI
    • Positron emission tomography (PET)
  • Neuropsychological tests

Other Tests & Protocols

  • Statistical parametric mapping (SPM).
  • Curry analysis.
  • Magnetoencephalography (MEG).

Assessment

Differential Diagnosis

  • Stroke
  • Brain Tumor
  • Brain or CNS infection
  • Cardiovascular disorder
  • Metabolic disorders
  • Drug toxicity
  • Drug withdrawal symptoms
  • Fever (especially in children)

Context

Comorbidities

  • Depression
  • Lowered cognitive functioning
  • Autism

Nutritional Considerations for Epilepsy

  • B12
  • B9
  • Antioxidants
  • Polyunsaturated fatty acids
  • Amino Acids
  • Tryptophan
  • Taurine
  • Carnosine
  • Vitamins A, C, & E
  • Zinc
  • GABA
  • Potassium
  • Calcium
  • Linoleic acid
  • Selenium

The Herbs

Materia Medica (9)

Herbs traditionally or clinically used for epilepsy.

Angelica

Angelica archangelica

Apiaceae
Urinary AntispasmodicAntispasmodicCarminativeBitter +4

Bacopa

Bacopa monnieri

Plantaginaceae
NootropicNervineAnticonvulsantAnxiolytic +2

Cannabis

Cannabis sativa

Cannabaceae
AnticonvulsantAntispasmodicAnalgesicAntiemetic +7

Cat's Claw

Uncaria tomentosa

Rubiaceae
ImmunomodulatorAnti-InflammatoryAntioxidantAdaptogen +6

German Chamomile

Matricaria chamomilla

Asteraceae
Anti-InflammatoryAntispasmodicAntiallergicAntibacterial +7

Gotu Kola

Centella asiatica

Apiaceae
NervineNeuroprotectiveNootropicVulnerary +11

Melissa

Melissa officinalis

Lamiaceae
NervineCarminativeAntispasmodicAntiviral +7

Passionflower

Passiflora incarnata

Passifloraceae
AnalgesicAntibacterialAntifungalAntidepressant +6

References:

  1. Beghi, E. (2004). Aetiology of epilepsy (p. 61). Blackwell Science, Oxford.