Compound Monograph
Tannins
Tannins are a broad class of astringent plant polyphenols that bind proteins, divided into hydrolysable and condensed types.
Classification
Tannins are a class of plant constituents. Astringent polyphenols that bind and precipitate proteins, tightening and toning tissue.
Where Does It Come From? (43)
Plants and supplements in the database that list tannins among their constituents.
Research & Evidence
Tannins are a large group of astringent polyphenols that bind and precipitate proteins, which gives tannin-rich foods and herbs their puckering, drying mouthfeel. They are conventionally divided into hydrolysable tannins (gallotannins and ellagitannins) and condensed tannins (proanthocyanidins). They underlie the traditional use of many astringent herbs for diarrhoea, sore throats and topical wound care, and they contribute antioxidant activity. Because the term covers many structurally diverse compounds, general claims describe the class rather than a single molecule.
Toxicity & Safety
At dietary levels tannins are generally well tolerated, though their protein-binding can reduce absorption of iron and some other nutrients and may cause stomach upset in large amounts. Very high or prolonged intake of certain tannins has been associated with adverse effects, so concentrated use over long periods is best avoided.